35 | CREATOR, FAMILY GUY, AMERICAN DAD, THE CLEVELAND SHOW, CAVALCADE OF CARTOON COMEDY

If Seth McFarlane hasn't officially assumed the title of Hardest-Working Man in Show Business, he certainly gets paid like he has. Over the past decade, the cartoon auteur has nimbly tap-danced his way from a breakthrough role as television's youngest executive producer to a star turn as its wealthiest one. A new $100 million contract will keep Family Guy (whose DVD sales have reached a gaudy $1 billion) and American Dad on Fox through 2012—and now, in his spare time, McFarlane is revolutionizing online advertising. His partnership with Google is sure to net him another fortune—he'll produce 50 two-minute cartoons (which he likens to "an animated 'Far Side'") that will be paired with, say, Burger King spots and be automatically syndicated to demographically suitable (i.e., dude-friendly) sites. But McFarlane insists he is a creative guy whose work is marketing-friendly, not the other way around. "Once you get into marketing, I glaze over a bit," he says. Only one aspect of all this multitasking and paradigm-shifting wears him out. "It's the number of voices I'm doing for all the shows," he says. "That's where I sometimes feel overwhelmed."

NEXT: Mary Parent, Chairperson, Worldwide Motion Picture Group, MGM
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