1. Johnny Depp/Tim Burton
One of the most iconic auteur/leading-man teams in Hollywood history has made seven films together, including the art-house favorite Ed Wood and the box-office hit Alice in Wonderland. According to Burton, they communicate in a way that "wouldn't really make sense to the normal person."

2. Robert de Montesquiou/Marcel Proust (and others)
Count Robert de Montesquiou-Fézensac did not so much live as perform his life: He was a fixture of 19th-century high society, and the Savile Row clotheshorse, lavish decorator, and infamous wit served as the inspiration for as many as five different fictional characters (including Proust's Baron Charlus in Remembrance of Things Past).

3. Jonathan Plummer/Terry McMillan
Writer Terry McMillan's vacation romance with Jonathan Plummer, a hotel-management employee more than 20 years her junior, would become the basis of her best-selling novel (and a subsequent movie) How Stella Got Her Groove Back. But after six years of marriage, Plummer announced that he was gay and penned his own roman à clef—about a young man's crumbling relationship with an oppressive older woman.

4. David Gandy/Dolce & Gabbana
In 2007, Dolce & Gabbana needed a face to represent Light Blue, the label's first men's fragrance in over a decade. Enter David Gandy, a British model who, in the ubiquitous ad, posed afloat on a raft displaying an impressively muscled abdomen—which helped earn the guy his very own D&G calendar, titled "David."

5. Lord Alfred Douglas/Oscar Wilde
When Oscar Wilde began a tempestuous love affair with Lord Alfred "Bosie" Douglas in the late 1800s, the playwright's life changed forever—and decidedly for the worse. It led to him being convicted of gross indecency (read: sodomy) and serving two years of hard time. Yet critics speculate that if it weren't for Bosie, Wilde might not written his gay-subtext-filled masterpiece The Importance of Being Earnest.

6. Kang Dong-won/Wooyoungmi
"[Kang] really matches everything that I have dreamed of," says the menswear designer Wooyoungmi of her muse. A fey, rail-thin South Korean actor, Kang is best known for playing emotionally tortured characters and, through his influence on Wooyoungmi, deserves a fair amount of credit for the influx of men you've seen this fall wearing loose double-breasted jackets and mournful expressions.

7. Neal Cassady/Jack Kerouac
Con man. Screwup. Serial charmer. Neal Cassady might have embodied the Zeitgeist of the fifties Beat generation, but it took Jack Kerouac to capture it on the page. Cassady's wayward past and ecstatic embrace of the present were rendered larger-than-life in the character of Dean Moriarty in On the Road, and the book made him the unofficial mascot of the era.

8. Joe Jonas/Taylor Swift
When Joe Jonas dumped Taylor Swift in 2008, his method wasn't exactly Disney-approved. "I'm not even going to be able to remember the boy who broke up with me over the phone in 25 seconds when I was 18," Swift said at the time. Yet heartbreak can help lead to great records. (Listen to the acid "Forever & Always.") In fact, Swift is more indebted to Jonas than she might care to admit, as evidenced by the JoBro-like sensibility (combining a touch of forgiveness with a lash of reprimand) that has come to define her career.