WHERE TO EAT
At Bar Strelka, the cocktail café of the Strelka Institute for Media, Architecture, and Design, on the island, you'll see iPads and smartphones scattered on the tables and models picking at salads while chatting up editors from Snob, the provocative culture magazine based nearby.
WHAT TO SEE
Revenue from Bar Strelka is funneled into the institute downstairs, where you might take in a lecture by influential design figures such as the partners of the famed Swiss architecture firm Herzog & de Meuron or enjoy a screening by an emerging Russian filmmaker. To add to the Eastern Bloc-SoHo vibe, there's a 3,000-square-foot art gallery/Italian joint called Art Akademiya (7-495-771-7446).
WHERE TO SLEEP
The city's newest boutique hotel, Red Zarya, recently opened on the island. Come for the cheap rooms (from $218) but stay for the scene.
WHERE TO DRINK
The quirky Rolling Stone Bar & Tattoo (7-495-504-0932) has an in-house tattoo parlor, while the Belka bar (7-495-768-5171) attracts a sexy crowd drawn to one of the few places in Moscow where you aren't allowed to smoke.
See more emerging neighborhoods.